High-resolution CT (HRCT) of the chest, also referred to as HRCT chest or HRCT of the lungs, refers to a CT technique in which thin-slice chest images are obtained and post-processed in a high-spatial-frequency reconstruction algorithm. This technique obtains images with exquisite lung detail, which are ideal for the assessment of diffuse interstitial lung disease. Idiopathic pulmonary fibrosis (IPF) is an entity of interstitial pneumonia that has an unfavorable prognosis; approximately 50% patients die within 2-5 years from diagnosis. Other connective tissue disease also present with pulmonary fibrosis pattern. HRCT could help to distingunish those diseases.